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Case Reports
. 1981 Oct;141(11):1544-5.

Seizures and dermatitis after exposure to caprolactam

S N Tuma, F Orson, F V Fossella, W Waidhofer
  • PMID: 7283571
Case Reports

Seizures and dermatitis after exposure to caprolactam

S N Tuma et al. Arch Intern Med. 1981 Oct.

Abstract

A 22-year-old man was initially seen with dermatitis, fever, and seizures after three days of occupational exposure to caprolactam, a nylon fiber precursor. A comprehensive neurological investigation showed no organic CNS abnormalities. Although caprolactam has been shown to induce convulsive disorders in experimental animals, to our knowledge, there are no reports of caprolactam-induced seizures in man. The coincidence of typical skin lesions with otherwise unexplained grand mal seizures in this strongly suggests that caprolactam was the cause.

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