[Cholesterol biosynthesis in the blood of rabbits with experimental atherosclerosis]
[Article in
Russian]
- PMID: 728610
Item in Clipboard
[Cholesterol biosynthesis in the blood of rabbits with experimental atherosclerosis]
[Article in
Russian]
Biull Eksp Biol Med.
1978 Dec.
Abstract
Blood of normal rabbits and those on atherogenic cholesterol diet was incubated with 2--14C-acetate of sodium. After incubation cholesterol and its precursors -- squalene and lanosterin -- were found and identified in the non-saponified fractions of leukocytes and platelets. The maximum specific activity was revealed in cholesterol, next in turn were lanosterin and squalene of leukocytes both in the normal rabbits and in those with atherosclerosis. In platelets the label was mainly accumulated in lanosterin.
Similar articles
-
Squalene, lanosterol and cholesterol synthesis from acetate in neonatal chick tissues.Rev Esp Fisiol. 1984 Dec;40(4):425-9. Rev Esp Fisiol. 1984. PMID: 6531508
-
Incorporation of 14C acetate into the sterols of rabbit lens in organ culture.Curr Eye Res. 1982-1983;2(9):607-11. doi: 10.3109/02713688208996361. Curr Eye Res. 1982. PMID: 7184713
-
Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro.J Biol Chem. 1973 Nov 10;248(21):7396-403. J Biol Chem. 1973. PMID: 4355579 No abstract available.
-
[Studies in the field of chemistry, biochemistry and photobiochemistry of sterols].Ukr Biokhim Zh. 1975 Sep-Oct;47(5):661-9. Ukr Biokhim Zh. 1975. PMID: 1105921 Review. Russian.
-
The intracellular organisation of cholesterol biosynthesis. A review.Steroids Lipids Res. 1972;3(4):236-56. Steroids Lipids Res. 1972. PMID: 4572325 Review. No abstract available.