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. 1981;37(8):892-4.
doi: 10.1007/BF01985699.

Thymidine: inhibitor of differentiation in the young chick blastoderm in culture

Thymidine: inhibitor of differentiation in the young chick blastoderm in culture

N Zagris et al. Experientia. 1981.

Abstract

Differentiation in the young chick blastoderm is affected by thymidine at concentrations higher than 8.2 x 10(-4) M. Blastoderms at the hypoblastic island stage cultured continuously in the presence of thymidine form an atypical primitive streak which is not capable of inducing the embryonic axis. However, blastoderms with a mature streak escape the effect of thymidine and develop normally.

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