Effect of wine on gastric emptying in humans

Abstract

The effect of wine on gastric emptying of meals was studied in 10 healthy male subjects. A dual radioisotopic method was employed utilizing isotope tracers added to the liquid (111In-diethyltriamine pentaacetic acid) and solid phases (99mT-tagged chicken liver) of the meal. In a random design subjects were fed two standardized 900-g meals containing 450 g of solid food ingredients and 450 g of either Cabernet Sauvignon (mean ethanol concentration = 9500 mg/dl) or low-alcohol Cabernet Sauvignon (mean ethanol concentration = 1312 mg/dl). In addition, 7 of the 10 subjects were fed wine and low-alcohol wine without solid food. Wine, when compared with low-alcohol wine, did not significantly alter gastric emptying of either liquid or solid food components.