Incidence rates of ulcerative colitis and Crohn's disease in fifteen areas of the United States

Abstract

A study was carried out during 1973 to determine the incidence of first hospitalizations for ulcerative colitis and Crohn's disease in 15 areas of the United States, including communities of widely varied size, climatic, ethnic, racial, and socioeconomic characteristics. The following descriptions apply to incidence rates per 100,000 population for the aggregate of the 15 areas. Ulcerative colitis had a bimodal age distribution in white males (with peaks at ages 20-29 and 70-79 yr) and females (with peaks at ages 30-39 and 70-79 yr). Crohn's disease had a bi- or trimodal age distribution in white males (with peaks at ages 20-29, 50-59, and 70-79 yr) and females (with peaks at ages 20-29, 50-59, and 70-79 yr). The age, sex, and geographic distributions that were observed in this study may have important etiologic implications.