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. 1981 Sep;33(3):834-9.
doi: 10.1128/iai.33.3.834-839.1981.

Adjuvant activity of carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs

I Azuma, H Okumura, I Saiki, M Kiso, A Hasegawa, Y Tanio, Y Yamamura

Adjuvant activity of carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs

I Azuma et al. Infect Immun. 1981 Sep.

Abstract

The adjuvant activity of 29 kinds of carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine was examined in guinea pigs. It was found that the D-manno- and D-galacto-type muramyldipeptides were as active as the D-gluco-type muramyldipeptide (MDP). The structural requirement of the carbohydrate moiety of analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine is discussed.

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References

    1. Biochem Biophys Res Commun. 1974 Aug 19;59(4):1317-25 - PubMed
    1. Biken J. 1975 Jun;18(2):105-11 - PubMed
    1. Biochem Biophys Res Commun. 1976 Sep 7;72(1):339-46 - PubMed
    1. Gan. 1976 Dec;67(6):867-77 - PubMed
    1. Ann Immunol (Paris). 1977 Apr-Jun;128C(3):653-61 - PubMed

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