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. 1981 Jul;34(7):783-90.
doi: 10.7164/antibiotics.34.783.

New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4

T Oki, Y Matsuzawa, K Kiyoshima, A Yoshimoto, H Naganawa, T Takeuchi, H Umezawa
Free article

New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4

T Oki et al. J Antibiot (Tokyo). 1981 Jul.
Free article

Abstract

Various blocked mutants were isolated from Streptomyces coeruleorubidus ME130-A4 by NTG and UV treatments. Among them, mutant strain 4N-140 produced new anthracycline feudomycins A and B having new aglycones in which the side chain at C-9 position of daunomycinone was ethyl and acetonyl, respectively. New aglycones feudomycinones C and D having methyl at C-9 and additional groups at C-10 of daunomycinone were also isolated from this strain.

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