Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981;2(1):19-32.
doi: 10.1080/01971528108062989.

A radioimmunoassay to measure cyclosporin A in plasma and serum samples

P Donatsch, E Abisch, M Homberger, R Traber, M Trapp, R Voges

A radioimmunoassay to measure cyclosporin A in plasma and serum samples

P Donatsch et al. J Immunoassay. 1981.

Abstract

A radioimmunoassay for the immunosuppressant drug Cyclosporin A has been developed which makes possible the monitoring of the drug by direct measurements in clinical plasma and serum samples. The antisera have been produced in rabbits using the hemisuccinate derivative of a structural analogue of Cyclosporin A as a hapten. The assay has both adequate specificity and sensitivity for Cyclosporin A to be suitable for the routine monitoring of therapy. Some degree of cross-reactivity has been shown to occur with four metabolites which were isolated from urine samples.

PubMed Disclaimer

LinkOut - more resources