Human interferon and its inducers: clinical program overview at Roswell Park Memorial Institute
- PMID: 728908
Human interferon and its inducers: clinical program overview at Roswell Park Memorial Institute
Abstract
An overview of the clinical interferon program at Roswell Park Memorial Institute is presented. Purified fibroblast interferon and a novel inducer of human interferon [rIn-r(C12,U)n] are being evaluated for possible antiviral, antiproliferative, and immunomodulatory activities in patients with cancer.
Similar articles
-
[Artificial polynucleotides as inducers of interferon].Z Gesamte Hyg. 1974 Feb;20(2):116. Z Gesamte Hyg. 1974. PMID: 4598964 Review. German. No abstract available.
-
[Interferon: its effects and clinical application].Internist (Berl). 1978 Dec;19(12):659-63. Internist (Berl). 1978. PMID: 370046 German. No abstract available.
-
[Perspectives on interferon research and on its therapeutic use].Arch Inst Pasteur Tunis. 1981 Sep-Dec;58(3):297-312. Arch Inst Pasteur Tunis. 1981. PMID: 6172080 French.
-
Production of the interferon protein: hyporesponsiveness.Tex Rep Biol Med. 1977;35:126-31. Tex Rep Biol Med. 1977. PMID: 358440 Review.
-
Effect of increasing thiolation of the polycytidylic acid strand of poly I:poly C on the alpha, beta and gamma interferon-inducing properties, antiviral and antiproliferative activities.Antiviral Res. 2004 Dec;64(3):171-7. doi: 10.1016/j.antiviral.2004.08.002. Antiviral Res. 2004. PMID: 15550270