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Case Reports
. 1981 Sep-Oct;4(5):363-6.
doi: 10.1002/mus.880040502.

Chronic tetanus: clinical report and histochemistry of muscle

W S Risk, E P Bosch, J Kimura, P A Cancilla, K H Fischbeck, R B Layzer
Case Reports

Chronic tetanus: clinical report and histochemistry of muscle

W S Risk et al. Muscle Nerve. 1981 Sep-Oct.

Abstract

A patient who was partially immune to tetanus developed nonfulminant tetanus after a minor injury. Manifestations of the disease persisted for over 17 months. Electrophysiologic studies revealed an absent silent period in the masseter muscle, large-amplitude F-responses, and denervation. A muscle biopsy showed neurogenic atrophy with reinnervation. This observation supports the existence of chronic tetanus and provides morphologic evidence for a peripheral action of tetanus toxin in humans.

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