Telemetry of cardiac left ventricular pressure in conscious dogs
- PMID: 7295919
Telemetry of cardiac left ventricular pressure in conscious dogs
Abstract
A fully implantable telemetric system for the measurement of cardiac left ventricular pressure and derived parameters in conscious dogs is presented. It provides the following advantages: ethical acceptability, scientific relevance, economical experimentation, avoidance of stress-induced situations for the animal, experiments without anaesthesia or sedation. The system has an operation time which allows the sequential pharmacological evaluation of a great number of drugs in individual dogs as has been shown by testing the effect of the positive inotropic agent, dobutamine, and the calcium antagonists, verapamil and nifedipine.
Similar articles
-
Simultaneous measurement of arterial and left ventricular pressure in conscious freely moving rats by telemetry.J Pharmacol Toxicol Methods. 2016 May-Jun;79:23-33. doi: 10.1016/j.vascn.2016.01.003. Epub 2016 Jan 9. J Pharmacol Toxicol Methods. 2016. PMID: 26778372
-
Doppler echocardiographic study of left and right ventricular function during dobutamine stress testing in conscious healthy dogs.Am J Vet Res. 1999 Jul;60(7):865-71. Am J Vet Res. 1999. PMID: 10407481
-
Physiologic response to dobutamine infusion during cardiac stress testing of dogs.Am J Vet Res. 1998 Sep;59(9):1160-5. Am J Vet Res. 1998. PMID: 9736396
-
Disparate force-frequency effects of pimobendan and dobutamine in conscious dogs with tachycardia-induced cardiomyopathy.J Card Fail. 2002 Dec;8(6):423-30. doi: 10.1054/jcaf.2002.129658. J Card Fail. 2002. PMID: 12528096
-
Implantable telemetry in biomedical research.IEEE Trans Biomed Eng. 1984 Dec;31(12):817-23. doi: 10.1109/TBME.1984.325243. IEEE Trans Biomed Eng. 1984. PMID: 6241176 Review. No abstract available.