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. 1981 May;19(5):386-9.
doi: 10.1111/j.1399-0004.1981.tb00730.x.

Erythrocyte catechol-O-methyltransferase activity in psychotic twins

Y Floderus, G Eberhard, L Witterberg

Erythrocyte catechol-O-methyltransferase activity in psychotic twins

Y Floderus et al. Clin Genet. 1981 May.

Abstract

Erythrocyte catechol-O-methyltransferase (COMT) activity was analyzed in 20 twin pairs, 6 monozygotic and 14 dizygotic, where one or both twins showed psychotic or prepsychotic symptoms. Fifteen of these pairs, 4 monozygotic and 11 dizygotic, were diagnosed as discordant for serious mental disturbance. The different psychotic states within twins did not seem to be associated with any difference in COMT activity.

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