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. 1978 Nov 24;58(1-2):71-7.
doi: 10.1007/BF00489951.

The effects of horseradish peroxidase on the concentration of 5-hydroxytryptamine and platelet counts in blood of rabbits and guinea pigs

R Haye, O V Sjaastad, A K Blom, T Vegge

The effects of horseradish peroxidase on the concentration of 5-hydroxytryptamine and platelet counts in blood of rabbits and guinea pigs

R Haye et al. Histochemistry. .

Abstract

When HRP was injected i.v. in rabbits and guinea pigs, a rapid fall in the number of circulating platelets and the concentration of 5 HT occurred. Platelet aggregates were trapped in lung capillaries. The aggregation was reversible and the return of platelets to the circulation concomitant with a rise in blood 5 HT concentration.

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