Clinical Trial
doi: 10.1016/s0140-6736(77)91540-9.
Treatment of acute viral hepatitis with (+)-cyanidanol-3
- PMID: 73062
- DOI: 10.1016/s0140-6736(77)91540-9
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Clinical Trial
Treatment of acute viral hepatitis with (+)-cyanidanol-3
Lancet.
.
Abstract
A double-blind trial of (+)-cyanidanol-3 (2 g/day) versus placebo tablets was carried out in 100 patients with acute viral hepatitis. 51 received the drug and 49 placebo. (+)-Cyanidanol-3 accelerated the disappearance of HBsAg from the blood, lowered serum-bilirubin, and relieved symptoms such as anorexia, nausea, and pruritus. The drug was well tolerated. None of the patients had a relapse of acute hepatitis. Chronic active hepatitis developed in 1 of the placebo-treated patients. Thus, (+)-cyanidanol-3 seems to be of benefit in acute viral hepatitis.
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