Dental enamel matrix: sequences of two amelogenin polypeptides
- PMID: 7306685
- DOI: 10.1007/BF01114799
Dental enamel matrix: sequences of two amelogenin polypeptides
Abstract
The amino acid sequences of a leucine-rich amelogenin polypeptide (LRAP) and a tyrosine-rich amelogenin polypeptide (TRAP), isolated from foetal bovine enamel matrix, were determined. Both LRAP and TRAP occurred in two forms; in each case, one of the molecular species appeared to be shortened at the COOH terminus by 2 and 4 residues, respectively. A striking finding was that LRAP and TRAP had identical sequences for the first 33 residues but were almost completely different for the remaining 12 amino acids.
Similar articles
-
Amelogenin post-translational modifications: carboxy-terminal processing and the phosphorylation of bovine and porcine "TRAP" and "LRAP" amelogenins.Biochem Biophys Res Commun. 1993 Nov 30;197(1):248-55. doi: 10.1006/bbrc.1993.2468. Biochem Biophys Res Commun. 1993. PMID: 8250931
-
Amelogenins. Sequence homologies in enamel-matrix proteins from three mammalian species.Biochem J. 1983 Apr 1;211(1):149-54. doi: 10.1042/bj2110149. Biochem J. 1983. PMID: 6870818 Free PMC article.
-
Enamel formation in vitro in mouse molar explants exposed to amelogenin polypeptides ATMP and LRAP on enamel development.Arch Oral Biol. 2007 Dec;52(12):1161-71. doi: 10.1016/j.archoralbio.2007.06.008. Epub 2007 Aug 6. Arch Oral Biol. 2007. PMID: 17679105
-
The enamelin/non-amelogenin problem. A brief review.Connect Tissue Res. 1989;22(1-4):93-100. Connect Tissue Res. 1989. PMID: 2689086 Review.
-
Description of two classes of proteinases from enamel extracellular matrix cleaving a recombinant amelogenin.Connect Tissue Res. 1996;35(1-4):231-8. doi: 10.3109/03008209609029196. Connect Tissue Res. 1996. PMID: 9084662 Review.
Cited by
-
Leucine rich amelogenin peptide alters ameloblast differentiation in vivo.Matrix Biol. 2013 Oct-Nov;32(7-8):432-42. doi: 10.1016/j.matbio.2013.05.004. Epub 2013 Jun 4. Matrix Biol. 2013. PMID: 23747796 Free PMC article.
-
Tooth Enamel and its Dynamic Protein Matrix.Int J Mol Sci. 2020 Jun 23;21(12):4458. doi: 10.3390/ijms21124458. Int J Mol Sci. 2020. PMID: 32585904 Free PMC article. Review.
-
Human amelogenins: sequences of "TRAP" molecules.Calcif Tissue Int. 1989 Oct;45(4):243-50. doi: 10.1007/BF02556044. Calcif Tissue Int. 1989. PMID: 2509010
-
Novel Mutations in GPR68 and SLC24A4 Cause Hypomaturation Amelogenesis Imperfecta.J Pers Med. 2021 Dec 28;12(1):13. doi: 10.3390/jpm12010013. J Pers Med. 2021. PMID: 35055328 Free PMC article.
-
Preferential and selective degradation and removal of amelogenin adsorbed on hydroxyapatites by MMP20 and KLK4 in vitro.Front Physiol. 2014 Jul 24;5:268. doi: 10.3389/fphys.2014.00268. eCollection 2014. Front Physiol. 2014. PMID: 25104939 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources