Studies of bile acid secretion by isolated rat hepatocytes
- PMID: 731133
Item in Clipboard
Studies of bile acid secretion by isolated rat hepatocytes
J Lipid Res.
1978 Nov.
Free article
Abstract
Bile acid secretion was studied in isolated rat hepatocytes cultured in medium supplemented with cofactors and succinate. Succinate as a respiratory substrate was found to be essential for bile acid synthesis. Feedback mechanism was demonstrated with different inhibitory potency of different bile acids on bile acid synthesis in isolated hepatocytes.
Similar articles
-
Effect of organic anions on bile acid uptake by isolated rat hepatocytes.Hoppe Seylers Z Physiol Chem. 1978 Aug;359(8):1027-30. doi: 10.1515/bchm.1978.359.1.181. Hoppe Seylers Z Physiol Chem. 1978. PMID: 711149 No abstract available.
-
Effect of albumin on bile acid uptake by isolated rat hepatocytes. Is there a common bile acid carrier?Biochem Biophys Res Commun. 1976 Nov 8;73(1):63-71. doi: 10.1016/0006-291x(76)90497-6. Biochem Biophys Res Commun. 1976. PMID: 999703 No abstract available.
-
Uptake of bile acids by perfused rat liver.Am J Physiol. 1976 Sep;231(3):734-42. doi: 10.1152/ajplegacy.1976.231.3.734. Am J Physiol. 1976. PMID: 788526
-
Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.J Pharmacol Exp Ther. 1995 Mar;272(3):1231-7. J Pharmacol Exp Ther. 1995. PMID: 7891338
-
The enterohepatic circulation of bile acids in man.Clin Gastroenterol. 1977 Jan;6(1):3-24. Clin Gastroenterol. 1977. PMID: 330051 Review.
Cited by
-
Transport systems of isolated hepatocytes. Studies on the transport of biliary compounds.Arch Toxicol. 1980 Mar;44(1-3):113-26. doi: 10.1007/BF00303188. Arch Toxicol. 1980. PMID: 7387394 No abstract available.
-
Stimulation of bile acid synthesis by dibutyryl cyclic AMP in isolated rat hepatocytes.Lipids. 1983 Jul;18(7):443-7. doi: 10.1007/BF02535783. Lipids. 1983. PMID: 6312238
-
Elevated biliary calmodulin during gallstone formation: the role of bile acids.Dig Dis Sci. 1998 Jan;43(1):170-7. doi: 10.1023/a:1018852810678. Dig Dis Sci. 1998. PMID: 9508521
-
Effect of spironolactone on p-nitrophenol glucuronidation in isolated rat hepatocytes.Experientia. 1983 May 15;39(5):527-8. doi: 10.1007/BF01965189. Experientia. 1983. PMID: 6406259
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
