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. 1978 Nov;19(8):985-91.

Studies of bile acid secretion by isolated rat hepatocytes

B Gardner, M S Chenouda
  • PMID: 731133
Free article

Studies of bile acid secretion by isolated rat hepatocytes

B Gardner et al. J Lipid Res. 1978 Nov.
Free article

Abstract

Bile acid secretion was studied in isolated rat hepatocytes cultured in medium supplemented with cofactors and succinate. Succinate as a respiratory substrate was found to be essential for bile acid synthesis. Feedback mechanism was demonstrated with different inhibitory potency of different bile acids on bile acid synthesis in isolated hepatocytes.

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