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Comparative Study
. 1981;28(4):359-65.

Formalin stress reaction of germfree and conventional mice treated with Bordetella pertussis vaccine

P Anderlik, M Wessely, I Szeri, Z Bános, I U Rápolthy, J Budai
  • PMID: 7315535
Comparative Study

Formalin stress reaction of germfree and conventional mice treated with Bordetella pertussis vaccine

P Anderlik et al. Acta Microbiol Acad Sci Hung. 1981.

Abstract

Germfree and conventional mice responded similarly to pertussis vaccine treatment. In both groups, lymphocytosis and splenomegaly developed in a similar proportion. The formalin stress reaction of germfree and conventional mice with hypertrophic lymphoid organs induced by pertussis vaccine differed from that of untreated mice: the treated germfree and conventional mice showed a acute increase of lymphocytosis without an significant change in splenomegaly.

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