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. 1981 Sep-Oct;44(5):530-5.
doi: 10.1021/np50017a003.

Antitumor agents. 49 tricin, kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, antileukemic principles from Wikstroemia indica

K H Lee, K Tagahara, H Suzuki, R Y Wu, M Haruna, I H Hall, H C Huang, K Ito, T Iida, J S Lai

Antitumor agents. 49 tricin, kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, antileukemic principles from Wikstroemia indica

K H Lee et al. J Nat Prod. 1981 Sep-Oct.

Abstract

Bioassay-directed isolation of the antitumor extract of Wikstroemia indica (Thymelaeaceae) has led to the characterization of tricin, kaempferol-3-O-beta-D-glucopyranoside, and (+)-nortrachelogenin as the major antileukemic constituents. In addition, daphnoretin was identified as the potent antitumor principle in vivo against the Ehrlich ascites carcinoma growth in mice.

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