[Effect of tubaside and sodium succinate on oxidative phosphorylation and p-hydroxylation in the liver]
- PMID: 7324195
[Effect of tubaside and sodium succinate on oxidative phosphorylation and p-hydroxylation in the liver]
Abstract
Tubaside causes disturbances in oxidative phosphorylation of the liver mitochondria. Sodium succinate administered during tubaside intoxication favours normalization of the oxygen uptake rate in state 3 and the ADP phosphorylation rate. Sodium succinate weakens the toxic effect of tubaside and favours normalization of p-hydroxylation in the liver. The animals, which were given tubaside in combination with sodium succinate are characterized by a higher survival rate.
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