doi: 10.1515/cclm.1981.19.12.1189.
Gas-liquid chromatographic determination of mexiletine in human serum with nitrogen sensitive detection
- PMID: 7328385
- DOI: 10.1515/cclm.1981.19.12.1189
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Gas-liquid chromatographic determination of mexiletine in human serum with nitrogen sensitive detection
J Clin Chem Clin Biochem.
1981 Dec.
Abstract
A simple and rapid method for the quantitative determination of mexiletine, using gas-liquid chromatography with nitrogen sensitive detection, is described. Only one extraction step is needed, the recovery is between 92-96% and the precision varies between 2.0--5.5%. The lower limit of detection reached 0.5 micro mol/1. During routine handling the method was easy, quick and cheap.
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