[Induced leukemias. Cytogenetical and cytological aspects. Comparison with primitive leukemias (author's transl)]

Abstract

25 presumably induced leukemias, either following treatment (lymphoma, polycythemia vera, essential thrombocythemia, cancers) or after exposure to oncogenic agents have been studied cytogenetically and cytologically. Complex chromosomal abnormalities were associated with a difficult cytological classification. Complete monosomy 7 with presence of micromegacaryocytes and macroplatelets was observed in 7 cases. The findings observed in induced leukemias were compared with those found in "primitive" leukemias showing the same chromosomal patterns. The same relationships between cytology and cytogenetics have been observed.