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. 1981 Dec;43(6):345-53.
doi: 10.1007/BF00320312.

Immunological changes following posttraumatic splenectomy

M Westerhausen, O Wörsdörfer, U Gessner, R De Giuli, H J Senn

Immunological changes following posttraumatic splenectomy

M Westerhausen et al. Blut. 1981 Dec.

Abstract

In 31 splenectomized individuals blood lymphocytes and serum immunoglobulins were examined 1-11 years after splenectomy. The results demonstrate: 1. Increase of the surface immunoglobulin bearing lymphocytes. 2. Reduction of the E-rosette forming lymphocytes, especially in a combined test assay. 3. Reduction of serum IgM. A surface-restoring effect of the RES of the spleen is discussed as a reason for the diminished E-rosette formation in splenectomized individuals.

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