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Comparative Study
. 1981 Dec 21;9(24):7041-51.
doi: 10.1093/nar/9.24.7041.

The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)

Comparative Study

The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)

R Lavery et al. Nucleic Acids Res. .

Abstract

The influence of the amino group of guanine on the molecular electrostatic potential and the accessibility to reactive sites of B-DNA is investigated by comparing the two model double helices poly (dI.dC) and poly (dG.dC). The calculations clarify the "disruptive" role of the guanine amino group on nucleic acid-polypeptide interactions.

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References

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