The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)
- PMID: 7335499
- PMCID: PMC327660
- DOI: 10.1093/nar/9.24.7041
The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)
Abstract
The influence of the amino group of guanine on the molecular electrostatic potential and the accessibility to reactive sites of B-DNA is investigated by comparing the two model double helices poly (dI.dC) and poly (dG.dC). The calculations clarify the "disruptive" role of the guanine amino group on nucleic acid-polypeptide interactions.
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