[Results of a multicenter orgotein study in radiation induced and interstitial cystitis]

Abstract

Thirty two patients suffering from radiation or interstitial cystitis were treated according to a method, first described by Marberger, Innsbruck. This method consists of intramural PeroxinormR (orgotein) injections into the bladder wall. The injections were administered during 4 to 6 weekly intervals and were given 1 to 6 times. The dose of injection was between 4 and 6 mg, mostly 12 mg, the total dose administered was between 8 and 72 mg. For the evaluation of the treatment objective and subjective criteria, such as cystoscopic picture, pain at rest, urgency, pollakisuria, incontinence, as well as bladder capacity and micturition frequency, during day and night, were used. In all patients a definite improvement in the symptoms could be observed. All the parameters and especially the bladder capacity and micturition frequency showed remarkable results. Orgotein treatment tolerability was found to be in 90% of the cases from very good to good.