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. 1981 Dec;12(4):556-60.

Increased circulating platelet aggregates in thalassaemia

  • PMID: 7344105

Increased circulating platelet aggregates in thalassaemia

P Winichagoon et al. Southeast Asian J Trop Med Public Health. 1981 Dec.

Abstract

Examination for circulating platelet aggregates according to Wu and Hoak revealed increased circulating platelet aggregates in 71% of splenectomized and 35% of nonsplenectomized patients with beta (0)-thalassaemia/Hb E disease. This may be causally related to the newly observed high incidences of pulmonary artery thrombosis and hypoxaemia in splenectomized thalassaemic patients. It is recommended that anti-platelet aggregation drugs such as aspirin and/or dipyridamole are given to thalassaemic patients after splenectomy.

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