Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981;22(3-4):391-402.
doi: 10.1186/BF03548664.

Alveld-producing saponins. I. Chemical studies

L Ceh, J G Hauge

Alveld-producing saponins. I. Chemical studies

L Ceh et al. Acta Vet Scand. 1981.

Abstract
in English, Swedish

Stabursvik (1959) described the saponin fraction of Narthecium ossifragum as a sarsasapogenin glycoside with the structure arabinosegalactose-xylose-glucose-sarsasapogenin. In a renewed study of the phototoxic lamb disease alveld, in which this saponin has been implicated (Ender 1955), we have looked more closely at the saponin fraction. We find that there are two saponins, one major and one minor. Both have a branched trisaccharide on C-3 of the sapogenin. Galactose is directly attached to C-3 in both saponins. The major saponin has glucose and arabinose attached to galactose, the minor saponin has glucose and xylose. We suggest the names narthecin and xylosin for the spirostanol form of these two saponins. In fresh juice from leaves we find little narthecin, however. Most of the saponin is present in the furostanol form, with glucose on C-26. Enzymatic hydrolysis showed this glucose to be bound as a β-glucoside. From specific rotations in partial hydrolysates we conclude that the saccharide on C-3 is a β-D-glucoside, α-L-araboside, β-D-galactoside.

Stabursvik (1959) bestemte saponinfraksjonen fra Narthecium ossifragum til å være et sarsasapogeninglykosid med struktur arabinose-galaktose-xylose-glukose-siarsasapogenin. I en fornyet studie av den fototoksiske lammesykdommen alveld, der dette saponin synes a spille en sentral rolle (Ender 1955) har vi undersøkt saponinfraksjonen nøyere. Vi finner at der er to saponiner, et hovedsaponin og et bisaponin. Begge har et forgrenet trisakkarid på sapogeninets C-3. Galaktose er direkte bundet til C-3 i begge saponiner. Hovedsaponinet har glukose og arabinose bundet til galaktose, bisaponinet har glukose og xylose. Vi foreslår navnene narthecin og xylosin for spirostanolformen av disse to saponiner. I frisk saft fra bladene finnes det imidlertid lite narthecin. Mesteparten av saponinet er til stede i furostanolformen, med et molekyl glukose bundet i C-26. Enzymatisk hydrolyse viste at denne glukose er bundet som β-glukosid. Fra spesifikke rotasjoner i partielle hydrolyseprodukter slutter vi at sakkaridet på C-3 er et β-D-glukosid, α-L-arabosid, β-D-galaktosid.

PubMed Disclaimer

References

    1. Boyden T W, Pamenter R W, Silvert M A. Testosterone secretion by the isolated canine testis after controlled infusions of HCG. J. Reprod. Fertil. 1980;59:25–30. doi: 10.1530/jrf.0.0590025. - DOI - PubMed
    1. Eik-Nes K B. Factors influencing the secretion of testosterone in the anaesthetized dog. Ciba Found. Colloq. Endocrinol. (Proc) 1967;16:120–136.
    1. Dufau M L, Watanabe K, Catt K J. Stimulation of cyclic AMP production by the rat testis during incubation with HCG in vitro. Endocrinology. 1973;92:6–11. doi: 10.1210/endo-92-1-6. - DOI - PubMed
    1. Lindner H R. Androgens and related compounds in the spermatic vein blood of domestic animals. I. Neutral steroids secreted by the bulls testis. J. Endocr. 1961;23:139–159. - PubMed
    1. Oltner, R., K. Lundstrøm & L. E. Edqvist: LH and testosterone in monozygous growing bulls. Swedish J. agric. Res. 1979, 9, 151– 161.

LinkOut - more resources