[Combined action of remantadine (amantadine) and ribavirin on experimental influenza]
- PMID: 7347232
[Combined action of remantadine (amantadine) and ribavirin on experimental influenza]
Abstract
The inhibiting effect of remantadine (amantadine) and ribavirin combination on experimental influenza infection was studied in comparison of the effect of each of these drugs alone. The combination of the two chemopreparations was found to inhibit synthesis of influenza A virus proteins in cell culture more effectively, to ensure maximum survival rate of white mice treated with these preparations by oral, aerosol and intraperitoneal routes of administration.
Similar articles
-
Amantadine and ribavirin aerosol treatment of influenza A and B infection in mice.Antimicrob Agents Chemother. 1980 Apr;17(4):642-8. doi: 10.1128/AAC.17.4.642. Antimicrob Agents Chemother. 1980. PMID: 7396454 Free PMC article.
-
[Effectiveness of a combination of remantadine and ribamide administered by aerosol in experimental influenzal infection in white mice].Vopr Virusol. 1982 Jul-Aug;27(4):440-4. Vopr Virusol. 1982. PMID: 7135923 Russian.
-
A comparison of test methods in influenza chemotherapy.J Antimicrob Chemother. 1975 Dec;1(4 Suppl):55-62. doi: 10.1093/jac/1.suppl_4.55. J Antimicrob Chemother. 1975. PMID: 1206032 No abstract available.
-
Ribavirin aerosol treatment of influenza.Infect Dis Clin North Am. 1987 Jun;1(2):441-57. Infect Dis Clin North Am. 1987. PMID: 3332797 Review.
-
[Antiviral agents in viral respiratory infections].Rev Chil Pediatr. 1988 May-Jun;59(3):192-9. Rev Chil Pediatr. 1988. PMID: 3075062 Review. Spanish. No abstract available.
Cited by
-
The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza A virus resistant to rimantadine (amantadine) in vitro and in vivo.Dokl Biochem Biophys. 2014 Mar;455(1):80-3. doi: 10.1134/S1607672914020100. Epub 2014 May 3. Dokl Biochem Biophys. 2014. PMID: 24795106 No abstract available.
-
High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination.J Med Virol. 1987 Feb;21(2):161-7. doi: 10.1002/jmv.1890210208. J Med Virol. 1987. PMID: 2434613 Free PMC article.