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. 1981 Feb;19(2):346-8.
doi: 10.1128/AAC.19.2.346.

Effects of ethambutol on phospholipid metabolism in Mycobacterium smegmatis

J O Kilburn, K Takayama, E L Armstrong, J Greenberg

Effects of ethambutol on phospholipid metabolism in Mycobacterium smegmatis

J O Kilburn et al. Antimicrob Agents Chemother. 1981 Feb.

Abstract

Soon after Mycobacterium smegmatis was exposed to ethambutol, the synthesis of cardiolipin and phosphatidylinositol dimannoside declined. The synthesis of phosphatidylethanolamine continued, but the drug caused this phospholipid to leak out of the cells.

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References

    1. Antimicrob Agents Chemother. 1977 Mar;11(3):534-40 - PubMed
    1. J Lipid Res. 1964 Jan;5:126-7 - PubMed
    1. Antimicrob Agents Chemother. 1979 Aug;16(2):240-2 - PubMed
    1. J Bacteriol. 1977 Nov;132(2):704-17 - PubMed

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