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Case Reports
. 1977 Oct;18(10):800-4.
doi: 10.1136/gut.18.10.800.

Myopathy in Whipple's disease

M Swash, M S Schwartz, M J Vandenburg, D J Pollock
Case Reports

Myopathy in Whipple's disease

M Swash et al. Gut. 1977 Oct.

Abstract

We report a patient with Whipple's disease who developed a myopathy that improved during antibiotic therapy. The muscle biopsy showed mild type 2 fibre atrophy, type 1 fibre preponderance, variability in fibre size, and changes in the myofibrillar pattern of affected fibres. Interfascicular macrophages contained PAS-positive material. With the electron microscope these macrophages contained membranous inclusions and bacillary bodies, similar to those seen in the jejunal biopsy.

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