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. 1978 Nov-Dec;24(6):762-5.

[Effect of hyperoxia combined with hydrocortisone administration on respiration of rat brain mitochondria]

[Article in Russian]
T T Podvigina, G V Troshikhin
  • PMID: 734976

[Effect of hyperoxia combined with hydrocortisone administration on respiration of rat brain mitochondria]

[Article in Russian]
T T Podvigina et al. Vopr Med Khim. 1978 Nov-Dec.

Abstract

After exposure of rats in oxygen atmosphere under pressure of 3 kgs/cm2 within 2 hrs phosphorylating respiration, respiratory control and the ratio ADP/O were decreased, while time of phosphorylation was increased in mitochondria of brain cortex. Content of 11-hydroxycorticosteroids was increased in blood plasma. Reaction of adrenal cortex to hyperbaric oxygenation was inhibited, if hydrocortisone was administered into animals within 1 hr before the treatment; in this case the patterns of mitochondrial function studied were similar to normal values.

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