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. 1980 Jan;52(1):41-6.
doi: 10.3171/jns.1980.52.1.0041.

Cerebrospinal fluid antibiotic levels during treatment of shunt infections

S L Wald, R L McLaurin

Cerebrospinal fluid antibiotic levels during treatment of shunt infections

S L Wald et al. J Neurosurg. 1980 Jan.

Abstract

Twenty patients with documented cerebrospinal fluid shunt infections were treated with daily intraventricular injections of methicillin, cephalothin, or gentamicin without removal of the shunt or external ventricular drainage. Periodic determinations of intraventricular antibiotic concentration revealed significant levels in relation to the established minimum inhibitory concentration in all cases.

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