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Clinical Trial
. 1980 Jan;96(1):132-5.
doi: 10.1016/s0022-3476(80)80349-0.

Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities

D Rudman, M Goldsmith, M Kutner, D Blackston
Clinical Trial

Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities

D Rudman et al. J Pediatr. 1980 Jan.

Abstract

The linear growth effects of oxandrolone, human growth hormone, and Ox + hGH were compared in six girls, age 11 to 15 years, with X chromosome abnormalities (three with X,O karyotype, three with Turner syndrome variants). Over six successive three-month periods, the patient received either no treatment, Ox, hGH, or Ox + hGH. The data demonstrate a significant (P less than 0.001) synergistic effect between Ox and hGH in stimulating linear growth in Turner syndrome and its variants.

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