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. 1980 Feb 8;207(4431):661-2.
doi: 10.1126/science.7352280.

Distribution of active gene sequences: a subset associated with tightly bound chromosomal proteins

D M Gates, I Bekhor

Distribution of active gene sequences: a subset associated with tightly bound chromosomal proteins

D M Gates et al. Science. .

Abstract

The distribution of active polyadenylate-messenger RNA sequences in fractionated chicken liver chromatin was examined. A portion of these active gene sequences is concentrated in a DNA fraction retained by tightly bound nonhistone chromosomal proteins, while the nonretained DNA fraction is substantially depleted of a portion of these sequences. These findings suggest that the tightly bound nonhistones are physically associated with a subset of active gene sequences.

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