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Comparative Study
. 1980 Feb 7;627(3):225-9.
doi: 10.1016/0304-4165(80)90451-1.

Vitamin K epoxidase activity of rough and smooth microsomes from rat liver

K Egeberg, L Helgeland
Comparative Study

Vitamin K epoxidase activity of rough and smooth microsomes from rat liver

K Egeberg et al. Biochim Biophys Acta. .

Abstract

The distribution of vitamin K epoxidase activity in rough and smooth microsomes has been studied and compared to the prothrombin precursor and vitamin K-dependent carboxylase activity. All three activities were high in rough microsomes as compared to the low levels found in smooth microsomes. The results are in agreement with the suggestion that there might be a linkage between the vitamin K-dependent carboxylation and epoxidation reaction in vivo.

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