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Comparative Study
. 1980 Jan;69(1):106-7.
doi: 10.1002/jps.2600690134.

Fluorescence assay of nitrofurantoin with o-aminothiophenol in plasma and urine

Comparative Study

Fluorescence assay of nitrofurantoin with o-aminothiophenol in plasma and urine

N Watari et al. J Pharm Sci. 1980 Jan.

Abstract

A fluorescence method is presented for the determination of nitrofurantoin based on conversion of the drug to a fluorescent substance. The method requires 0.1-0.5 ml of plasma or diluted urine and is 10 times more sensitive than the commonly used colorimetric method.

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