Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980;49(1):51-5.
doi: 10.1007/BF00692219.

Light microscopic study of striated muscle in uremia

R E Ahonen

Light microscopic study of striated muscle in uremia

R E Ahonen. Acta Neuropathol. 1980.

Abstract

Gastrocnemius muscle biopsies from 28 patients with chronic renal failure were analyzed with a light microscope after staining with Gomori trichrome stain and after histochemical reactions for ATPase and NADH diaphorase. Nineteen (68%) of the biopsies were pathological. Uremic myopathy was seen in eleven (39%) of the biopsies, eight of which were obtained from subjects on regular hemodialysis. Pure myopathic muscle damage was observed in three (11%), both myopathic and neuropathic muscle damage in eight (29%) and pure neuropathic muscle damage in eight (29%) of the biopsies. Fiber type atrophy and hypertrophy of both types were seen. The most common quantitative findings were Type II atrophy, small mean size and type grouping of Type II fibers, and Type I hypertrophy.

PubMed Disclaimer

References

    1. Johns Hopkins Med J. 1969 Feb;124(2):66-86 - PubMed
    1. Ann Intern Med. 1969 Jul;71(1):129-38 - PubMed
    1. J Appl Physiol. 1972 Sep;33(3):312-9 - PubMed
    1. Ann Rheum Dis. 1965 Sep;24(5):465-72 - PubMed
    1. Johns Hopkins Med J. 1968 Oct;123(4):158-73 - PubMed