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Clinical Trial
. 1980 Feb;9(2):165-9.
doi: 10.1111/j.1365-2125.1980.tb05828.x.

Response of pathological ischaemic muscle pain to analgesics

G Sacchetti, R Lampugnani, C Battistini, V Mandelli
Clinical Trial

Response of pathological ischaemic muscle pain to analgesics

G Sacchetti et al. Br J Clin Pharmacol. 1980 Feb.

Abstract

1 Twenty-four patients suffering from severe pain due to chronic occlusive arterial disease of the legs were given oral doses of indoprofen (200 mg), ibuprofen (300 mg) and placebo. 2 Differences in pain intensity scored on a five-point scale were taken as measurement of pain relief. 3 This double-blind, cross-over trial showed that indoprofen had significantly greater analgesic effect than placebo and reference drug. 4 From a methodological point of view there are many arguments on favour of pathological ischaemic pain as a test for clinical assessment of analgesics.

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References

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