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. 1980 Jan;68(1):14-6.
doi: 10.1111/j.1476-5381.1980.tb10691.x.

Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes

R Carnuccio, M Di Rosa, P Persico

Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes

R Carnuccio et al. Br J Pharmacol. 1980 Jan.

Abstract

Rat peritoneal luecocytes incubated with hydrocortisone (10 micrograms/ml) release a factor which inhibits prostaglandin generation. The steroid-induced inhibitor, which mediates the anti-phospholipase effect of antiinflammatory steroids, may be a protein or a polypeptide since its formation is blocked by cycloheximide, a known inhibitor of protein synthesis.

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References

    1. Metabolism. 1974 Feb;23(2):159-202 - PubMed
    1. Br J Pharmacol. 1975 Apr;53(4):539-46 - PubMed
    1. Biochem Pharmacol. 1976 Feb 1;25(3):285-91 - PubMed
    1. Nature. 1978 Jun 15;273(5663):552-4 - PubMed
    1. Nature. 1979 Mar 29;278(5703):456-9 - PubMed

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