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Case Reports
. 1980 Feb 15;45(4):808-10.
doi: 10.1002/1097-0142(19800215)45:4<808::aid-cncr2820450433>3.0.co;2-c.

Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease

J A Green, S L Spruance, B D Cheson
Case Reports

Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease

J A Green et al. Cancer. .

Abstract

The current report describes severe, multi-focal central nervous system (CNS) toxoplasmosis in a patient with untreated Hodgkin's disease. Anti-toxoplasma therapy was associated with prompt clinical improvement, and as such may represent the first successfully treated case of global CNS-toxoplasmosis occurring in a person with histologically documented lymphoma. Previously, CNS-toxoplasmosis has been noted to complicate lymphomas after initiation of anti-neoplastic therapy. The occurrence of disseminated toxoplasmosis prior to anti-neoplastic therapy is unique and suggests that lymphoma per se is a predisposing factor.

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