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. 1980 Jan;8(2):193-209.
doi: 10.1016/0378-1119(80)90037-2.

Genetic mapping of bovine mitochondrial DNA from a single animal

Genetic mapping of bovine mitochondrial DNA from a single animal

W W Hauswirth et al. Gene. 1980 Jan.

Abstract

Using a physical map of bovine mitochondrial DNA derived from the liver of a single Holstein cow, we have determined the location of the genes specifying the large and small ribosomal RNAs by hybridization analysis and electron microscopic observations of R-loop forms. Also, the position of the origin of DNA replication (D-loop) has been located by electron microscopy. Additionally, the direction of D-loop expansion and the polarity of the large and small ribosomal RNA genes were determined.

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