Immunochemical studies of the lipopolysaccharides of Vibrio cholerae: constitution of O specific side chain and core polysaccharide

Abstract

Lipopolysaccharides from various strains of Vibrio cholerae have been found to consist of distinct O-specific side chain and core polysaccharide regions in their degraded polysaccharides. The major identifiable components in the core polysaccharide were phosphorus, glucose, heptose, fructose, and ethanolamine phosphate, with small amounts or traces of mannose, rhamnose, and D-perosamine. On the other hand, glucose, fructose, mannose, rhamnose, glucosamine, D-quinovosamine, and D-perosamine were identified from O-specific side chain polysaccharide. The amounts of each component have been determined from O-specific side chain and core polysaccharides of the lipopolysaccharides from these bacterial strains.