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Clinical Trial
. 1980;37(3):149-51.
doi: 10.1159/000225424.

An evaluation of two schedules of VP-16 and adriamycin in patients with advanced breast cancer

J Rubin, D A Decker, D L Ahmann, R T Eagan, J N Ingle, R G Hahn
Clinical Trial

An evaluation of two schedules of VP-16 and adriamycin in patients with advanced breast cancer

J Rubin et al. Oncology. 1980.

Abstract

A phase II study utilizing VP-16 and adriamycin in a randomized fashion tested the concept of synchronization of the drugs in treatment of metastatic breast cancer. Although there was a trend in median survival following the synchronized schedule, there was no significant difference in survival or progression-free intervals. The concept of synchronization was not established.

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