Efficacy of injectable and tablet formulations of praziquantel against mature Echinococcus granulosus

Abstract

The efficacy of an injectable formulation of praziquantel (given either intramuscularly or subcutaneously at dose levels of 5 or 8 mg/kg of body weight) and a tablet formulation (5 mg/kg) against mature Echinococcus granulosus tapeworms was studied in experimentally infected dogs. The compound was efficacious (100% clearance) if injected via either route or if administered orally.