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Case Reports
. 1980 Feb;17(1):44-7.
doi: 10.1136/jmg.17.1.44.

High resolution of a small pericentric inversion of chromosome 11

H Autio-Harmainen, A De La Chapelle
Case Reports

High resolution of a small pericentric inversion of chromosome 11

H Autio-Harmainen et al. J Med Genet. 1980 Feb.

Abstract

A pericentric inversion 11 (p11q13.3) segragating in two generations is described. A high degree of resolution of the inversion was achieved by using prophase and prometaphase chromosomes from methotrexate-synchronised cells. The inversion occurred in a mother and three of her ten children. It had no detectable clinical consequences.

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