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. 1978 Oct 1;175(1):333-6.
doi: 10.1042/bj1750333.

Dissociation of fibronectin from gelatin-agarose by amino compounds

M Vuento, A Vaheri

Dissociation of fibronectin from gelatin-agarose by amino compounds

M Vuento et al. Biochem J. .

Abstract

Soluble fibronectin of human plasma was specifically dissociated at neutral pH from gelatin-agarose by several cationic amino compounds, notably the polyamines spermine, spermidine and putrescine, the basic amino acid arginine, and amino sugars. The neutral and acidic amino acids and the N-acetylated derivatives of amino sugars tested were ineffective. Gel-filtration experiments demonstrated that [14C]spermidine bound to fibronectin but not to gelatin.

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