Comparative Study
[Energy metabolism and myocardial contractile activity in cardiocytotoxic injury]
[Article in
Russian]
- PMID: 7370410
Item in Clipboard
Comparative Study
[Energy metabolism and myocardial contractile activity in cardiocytotoxic injury]
[Article in
Russian]
Biull Eksp Biol Med.
1980 Feb.
Abstract
It was established in experiments on anesthetized dogs with a closed thorax that injection of anticardiac cytotoxix serum into one of the main branches of the left coronary artery is accompanied by regional disturbances of energy metabolism, manifested by a decrease in ATP, ADP, AMP and glycogen content, and in the contractility of a injured area of the left ventricle. Undamaged myocardium of the left and right ventricles showed a compensatory hyperfunction and an increased level of noradrenaline. The energy metabolism parameters of undamaged cardiac area do not undergo any material changes.
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