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. 1978 Dec;13(6):709-18.

Aluminum levels in brain in Alzheimer's disease

G A Trapp, G D Miner, R L Zimmerman, A R Mastri, L L Heston
  • PMID: 737258

Aluminum levels in brain in Alzheimer's disease

G A Trapp et al. Biol Psychiatry. 1978 Dec.

Abstract

In both human Alzheimer's disease and aluminum encephalopathy of animals, changes are observed in neurofibrillary structures. We have found that brains from Alzheimer patients contain approximately 1.4 times the aluminum level found in a control series. Some possible methodological problems are discussed. We have proposed a plausible chemical mechanism for the changes of aluminum encephalopathy.

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