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. 1980 Feb;116(2):539-43.
doi: 10.1099/00221287-116-2-539.

Sterol requirement for the growth of Treponema hyodysenteriae

R M Lemcke, M R Burrows

Sterol requirement for the growth of Treponema hyodysenteriae

R M Lemcke et al. J Gen Microbiol. 1980 Feb.

Abstract

The addition of cholesterol to a liquid medium containing bovine serum albumin (BSA) fraction V or acetone-delipidized BSA fraction V instead of serum stimulated the growth of Treponema hyodysenteriae, a serum-requiring spirochaete associated with swine dysentery. As little as 1.25 micrograms cholesterol ml-1 increased viable counts about 1000-fold. Sitosterol and cholestanol, but not pregnenalone, cholestenone or stigmasteriol, produced a growth response comparable to that of cholesterol. The results suggest that T. hyodysenteriae requires a sterol for growth.

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