Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Jan;55(1):43-5.
doi: 10.1136/adc.55.1.43.

Serum ferritin, liver iron stores, and liver histology in children with thalassaemia

S de Virgiliis, G Sanna, G Cornacchia, F Argiolu, V Murgia, M Porcu, A Cao

Serum ferritin, liver iron stores, and liver histology in children with thalassaemia

S de Virgiliis et al. Arch Dis Child. 1980 Jan.

Abstract

Serum ferritin, liver iron stores, and liver histology were studied in 38 children with thalassaemia major who were being treated by regular blood transfusions. There was no correlation between serum ferritin levels and either the number of transfusions or the amount of iron deposited in the liver. However, for a given level of iron stores, ferritin levels were higher in patients with chronic hepatitis (including chronic aggressive and chronic persistent forms) than in those with hepatic siderosis only. We conclude that serum ferritin reflects tissue iron deposits in regularly transfused thalassaemic patients, only in the absence of hepatitis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lancet. 1968 Sep 14;2(7568):626-8 - PubMed
    1. J Clin Invest. 1969 Nov;47(11):2512-22 - PubMed
    1. J Clin Pathol. 1972 Apr;25(4):326-9 - PubMed
    1. Br Med J. 1972 Oct 28;4(5834):206-8 - PubMed
    1. N Engl J Med. 1974 May 30;290(22):1213-6 - PubMed

LinkOut - more resources